Irf7 mouse
WebNov 30, 2024 · IRF7 could regulate the transcription of Usp25 in mouse embryonic fibroblast (MEFs) and BM-derived dendritic cells (BMDCs) in response to viral infection or LPS. 42 It was reported that Usp25 binds with the promoter of Sox2 that played an important role in the pluripotency of embryonic stem cells development. 43, 44 Whether Usp25 is a potential ... WebJul 7, 2024 · It remains possible that IRF7, a homolog of IRF3, compensates for the loss of IRF3 and explains the IRF3-independent resistance to HSV-1 that we observe. ... Mouse primary microglia cells and ...
Irf7 mouse
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WebIRF7 Antibodies Antibodies that detect IRF7 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Flow Cytometry, Immunocytochemistry … WebMar 7, 2024 · AML-IRF7 −/− mice exhibited accelerated disease progression with intracerebral invasion of AML cells. AML-IRF7 −/− cells showed increased proliferation and elevated leukemia stem cell (LSC)...
IRF7 encodes interferon regulatory factor 7, a member of the interferon regulatory transcription factor (IRF) family. IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including the type I interferon genes. In particular, IRF7 regulates many interferon-alpha genes. Constitutive expression of IRF7 is largely restricted to lymphoid tissue, largely plasmacytoid dendritic cells, whereas IRF7 is inducible in many tissues. Multiple IRF7 tra…
WebJul 14, 2016 · IRF3-5D, an active form of IRF3, and IRF7Δ247–467, a constitutively active form of IRF7 were constructed as previously described using pFLAG-IRF3, and pFLAG-IRF7 plasmids as templates 38,39,40 ... WebMouse Antibody Type Monoclonal Host Species Rat Immunogen Partial mouse IRF7 recombinant protein (127-487a.a.) expressed in E. coli. Formulation Phosphate-buffered …
WebImmunohistochemistry-Paraffin: IRF7 Antibody (SC0617) [NBP2-67634] - Analysis of paraffin-embedded mouse liver tissue using anti-IRF7 antibody. Counter stained with hematoxylin. Flow Cytometry: IRF7 Antibody (SC0617) [NBP2-67634] - Analysis of Jurkat cells with IRF7 antibody at 1/50 dilution (red) compared with an unlabelled control (cells ...
WebUse of MICE by companies or for-profit entities requires a license prior to shipping. Licensing Information Phone: 207-288-6470 Email: [email protected] Payment Terms and Conditions Terms are granted by individual review and stated … biotage south walesWebProduct Details. Partial mouse IRF7 recombinant protein (127-487a.a.) expressed in E. coli. Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide. The antibody was purified by affinity chromatography. The antibody solution should be stored undiluted between 2°C and 8°C. biotainer manifoldWebUsing the International Mouse Strain Resource Mouse lines carrying: Irf7 tm1Ttg mutation (2 available); any Irf7 mutation (16 available) ♀ phenotype observed in females biotainer biontechWebJun 19, 2024 · To elucidate pDC immunomodulatory functions, we developed a mouse model in which IRF7 signaling is restricted to pDC. Despite undetectable levels of IFN-I protein, pDC-restricted IRF7 signaling controlled both viruses and was sufficient to protect mice from lethal CHIKV infection. Early pDC IRF7-signaling resulted in amplification of … biotainer capsWebIRF7 is a lymphoid-specific factor, which is constitutively expressed in the cytoplasm in B cells, pDCs and monocytes in the spleen, thymus, and peripheral blood lymphocytes, and … biota holdings pty ltdWebIn this study, we analyzed the role of IRF3 and IRF7 for the host response to IAV infections in Irf3-/-, Irf7-/-, and Irf3-/-Irf7-/- knockout mice. While the absence of IRF3 had only a … biotainer pcWebJan 10, 2024 · IRF7 is the key transcription factor which induces IFNα expression 9, leading to a second wave of type I IFN release. Since IFNα signals via the IFNAR this leads to a positive feedback loop that... biotain pc 3233-42